대한대장항문학회

<b>Purpose:</b> The liver and lung are the most common site of metastases after curative resection of colorectal carcinoma, and only 10 months of median survival is achieved once metastases has occurred in the lung. About 10% of patients have a<br>solitary<br>pulmonary metastasis and surgical resection leads to a 5 year survival rate of 21∼43%. We have tried to define ideal candidates for pulmonary resection in a patient with pulmonary metastases from colorectal carcinoma. <b>Methods:</b> Between<br>March<br>1990<br>to Feb. 2001, 25 patients underwent pulmonary resection for metastatic colorectal carcinoma. 15 patients were male, and 10 were female with mean age of 60.0 (range, 36∼73) years. The primary sites were colon in 7 patients and rectum in 18<br>patients.<br><b>Results:</b> The mean disease free interval was 30.04±19.79 (range, 1∼84) months and 19 patients had single metastasis and 6 patients had multiple metastatic lesions. Twenty-one patients had unilateral lesion. Wedge resection was done in 10<br>patients, lobectomy in 7, pneumonectomy in 2, wedge resection with bilobectomy in 2, segmentectomy and wedge resection in 1, and segmentectomy and lobectomy in 1 patient. Six patients recurred mean 13.7 months after the first operation (range,<br>1∼33<br>months) and they underwent wedge resection in 4 and one case each of lobectomy and segmentectomy. Seven patients died during follow up with 3 year survival rate of 70.8% and 5 year survival rate of 43.4%. <b>Conclusions:</b> The disease free<br>interval,<br>number of metastases, type and location of pulmonary resection, level of carcinoembryonic antigen had no correlation with the survival rate. We conclude that surgical resection of colorectal lung metastases is safe and effective, and every<br>patients<br>should be evaluated as a surgical candidate.<br>