대한대장항문학회

Familial Adenomatous Polyposis (FAP) is a rare and autosomal dominantly inherited<br>disorder characterized by the development of hundreds to thousands of colorectal polyps.<br>Korean Polyposis Registry was established in July, 1990 for early detection and management<br>of the FAP patient. Recently, we have experienced in our institution a case of the FAP family<br>kindred living in Jeju Island of Korea. Their relatives have been managed for the past 20<br>years and are listed in the Korean polyposis registry. Pathologic diagnosis of our proband<br>was stage III (T3N1M0) rectal cancer with thousands of colonic polyps. Intrafamilial strife<br>and psychologic distress was significant due to the late detection and progression to rectal<br>cancer. Therefore, we reviewed our case of the FAP family with literature regarding the<br>psychologic distress and the role of the regional registry.<br>