대한대장항문학회

We examined the interrelationships of depth of penetration, tumor size, and<br>the<br>number of positive lymph nodes in Dukes'c colorectal cancer. This report contains a<br>retrospective study of 256 cases of colorectal cancer that underwent treatment from Jan.<br>1985 to Dec. 1994 at the Department of Surgery, Kangbuk Samsung Hospital. The most<br>of the patients were on the 6th decades and male to female ratio was 1.27 : 1. By<br>modified Astler-Coller classification, there were stage Cl 29 cases(11.3%), C2<br>227<br>cases(88.7%). Eighty patients with colon cancer(31.4%) and 176 patients with carcinoma<br>of the rectum(68.6%) were available for analysis. Utilizing cumulative frequency<br>distributions of tumor size, depth of invasion and the number of positive lymph nodes,<br>comparisons were carried out among three factors.<br>The results indicate that there was no correlation between the longest diameter of the<br>tumor and other two factors but the number of positive lymph node was closely related<br>to depth of invasion.<br>In conclusion, the number of positive lymph node and depth of invasion are very<br>important prognostic factor. But tumor size as a single factor does not correlated with<br>prognosis in Dukes' C colorectal cancer.<br>