대한대장항문학회

A clinical evaluation and follow up for the results on 13 patients with liver metastatic<br>tumor from colorectal cancer who were performed hepatic resection at the Department of<br>General Surgery, Hanyang University Hospital from March, 1987 to March, 1993, have<br>been analyzed.<br>The results were follows;<br>1) The primary lesion was colon in 6 cases, rectum in 7 cases and almost all<br>advanced stage as 1 case was Dukes' B2 and others Dukes' C2.<br>2) The liver metastases was found synchronously in 7 cases, metachronously in 6<br>cases, and all synchronous cases were resected synchronously.<br>3) The location of liver metastases was single metastases in 6 cases, multiple<br>metastases in 7 cases and unilobar metastases in 9 cases, bilobar metastases in 4 cases.<br>4) In operative findings, no evidence of porta hepatis invasion and tumor was well<br>encapsulated in 7 cases.<br>5) In operative method, major hepatic resection was done in 6 cases and in 4 of 6<br>cases have no evidence of recurrence during 10∼36 months.<br>6) In adjuvant therapy, systemic chemotherapy was done in 6 cases, combination of<br>systmeic and hepatic-arterial chemotherapy in 4 cases, radiation therapy in 1 case.<br>And 2 of 4 Patients after combination therapy have no evidence of recurrence during<br>24, 34 months.<br>7) The mean survival period was 14 months and the survival rate was 0.39 during 36<br>months with Kaplan-Meier equation.<br>8) During above period, all Patients received hepatic resection both synchronously or<br>metachronously metastasized.<br>The results of this study demonstrate that almost all metastatic hepatoma was not<br>combined with liver cirrhosis and had normal liver function, major hepatic resection was<br>appliable and adjuvant therapy indicated as remnant liver functions were normal. In<br>diagnosis and treatment of metastatic hepatoma, aggressive attitude is needed.<br>