대한대장항문학회

Familial adenomatous polyposis is a rare hereditary disorder characterized by the<br>development of multiple adenomatous polyps throughout the colon and rectum which, if<br>untreated, will uniformaly degenerate into colon cancer. So, Prophylactic surgery should<br>be Performed. We analyzed retrospctively 8 patients of familial adenomatous polyposis<br>who were treated surgically at the Department of surgery, Koryo General Hospital, from<br>January 1982 to December 1991.<br>The results were as follows:<br>1) The peak age incidence was 4 th decade and the ratio between male and female<br>was 3:1.<br>2) In 7 of S cases had family history.<br>3) The clinical manifestation were mainly bloody stool and diarrhea, defecation<br>difficulty, bowel habit chance. In 5 of 8 cases(62.5%) were admitted to our hospital<br>within 1 rear after onset of symptoms.<br>4) The diagnosis was made with digital examination, barium enema, sigmoidoscopy<br>and colonoscopy. Colonoscopy was the most valuable method.<br>5) As for operative procedures, total proctocolectomy and ileostomy was done in 2<br>cases, subtotal colectomy and colostomy in 2 cases, left hemicolectomy in 1 cases and<br>total colectomy and ileoproctostomy in 3 cases.<br>6) The incidence of associated cancer was not correlated with number of polyps.<br>7) The postoperative complications were developed in 2 cases which were wound<br>infection and intestinal obstruction.<br>8) In 2 of 8 cases were died of distant metastasis.(mean follow up:2.8 years)<br>9) In 2 of 3 cases who received total colectomy and ileoproctostomy, the remained<br>polyps in rectum were regressed spontaneously.<br>